Pitofenone-d4
Pitofenone-d4 is deuterium labeled Pitofenone (HY-105853) . Pitofenone, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively[1][2].
Product Specifications
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C(C2=CC=C(C=C2)OC([2H])([2H])C([2H])([2H])N3CCCCC3)=O)C=CC=C1)OC
Molecular Formula
C22H21D4NO4
Molecular Weight
371.46
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Punekar NS, et al. Acetylcholinesterase inhibition by pitofenone: a spasmolytic compound. Biotechnol Appl Biochem. 1991 Dec;14 (3) :378-82.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-105853S/
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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