WAY 629

WAY 629 is a potent and selective 5-HT2C agonist with EC50s of 426, 260000 nM for 5-HT2C and 5-HT2A, respectively. WAY 629 decreases feeding behavior[1][2].

Product Specifications

CAS Number

[57756-45-3]

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/way-629.html

Solubility

10 mM in DMSO

Smiles

N1(CCNC2)C3=C(C4=CC=CC2=C41)CCCC3

Molecular Formula

C15H18N2

Molecular Weight

226.32

References & Citations

[1]Sabb AL, et al. Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor. Bioorg Med Chem Lett. 2004 May 17;14 (10) :2603-7. |[2]Aoki M, et al. Involvement of serotonin 2C receptor RNA editing in accumbal neuropeptide Y expression and behavioural despair. Eur J Neurosci. 2016 May;43 (9) :1219-28.