Cyclo (Arg-Gly-Asp-D-Phe-Val)

<strong>cyclo(Arg-Gly-Asp-D-Phe-Val)</strong> <strong>Catalog number:</strong> MDP0676 <strong>CAS Number: </strong>133343-34-7 <strong>Sequence: </strong>cyclo(Arg-Gly-Asp-D-Phe-Val) <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 574.4 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Chatterjee S, Brite KH, Matsumura A. Induction of apoptosis of integrin-expressing human prostate cancer cells by cyclic Arg-Gly-Asp peptides Clin Cancer Res. 2001 Oct;7(10):3006-11. 2: Haubner R, Wester HJ, Reuning U, Senekowitsch-Schmidtke R, Diefenbach B, Kessler H, Stöcklin G, Schwaiger M. Radiolabeled alpha(v)beta3 integrin antagonists: a new class of tracers for tumor targeting J Nucl Med. 1999 Jun;40(6):1061-71. 3: Bae HB, Zmijewski JW, Deshane JS, Zhi D, Thompson LC, Peterson CB, Chaplin DD, Abraham E. Vitronectin inhibits neutrophil apoptosis through activation of integrin-associated signaling pathways Am J Respir Cell Mol Biol. 2012 Jun;46(6):790-6. 4: Emmrich JV, Hornik TC, Neher JJ, Brown GC. Rotenone induces neuronal death by microglial phagocytosis of neurons FEBS J. 2013 Oct;280(20):5030-8. 5: Asakawa D, Smargiasso N, De Pauw E. Estimation of peptide N-Cα bond cleavage efficiency during MALDI-ISD using a cyclic peptide J Mass Spectrom. 2016 May;51(5):323-7. 6: Chatterjee S, Matsumura A, Schradermeier J, Gillespie GY. Human malignant glioma therapy using anti-alpha(v)beta3 integrin agents J Neurooncol. 2000;46(2):135-44. 7: Mey L, Hörmann M, Schleicher N, Reuter P, Dönges S, Kinscherf R, Gassmann M, Gerriets T, Al-Fakhri N. Neuropilin-1 modulates vascular endothelial growth factor-induced poly(ADP-ribose)-polymerase leading to reduced cerebrovascular apoptosis Neurobiol Dis. 2013 Nov;59:111-25. 8: Ren X, Xu J, Cooper JP, Kang MH, Erdreich-Epstein A. c-Abl is an upstream regulator of acid sphingomyelinase in apoptosis induced by inhibition of integrins αvβ3 and αvβ5 PLoS One. 2012;7(8):e42291. 9: Shen ZH, Zeng DF, Wang XY, Ma YY, Zhang X, Kong PY. Targeting of the leukemia microenvironment by c(RGDfV) overcomes the resistance to chemotherapy in acute myeloid leukemia in biomimetic polystyrene scaffolds Oncol Lett. 2016 Nov;12(5):3278-3284. <a href="https://pubmed.ncbi.nlm.nih.gov/19563408">10: Hou L, Mori D, Takase Y, Meihua P, Kai K, Tokunaga O. Fumagillin inhibits colorectal cancer growth and metastasis in mice: in vivo and in vitro study of anti-angiogenesis Pathol Int. 2009 Jul;59(7):448-61. </a> <br><strong>Products Related to cyclo(Arg-Gly-Asp-D-Phe-Val) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>