AGN 193109 (GMP)
AGN 193109 (GMP) is AGN 193109 (HY-U00449) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. AGN 193109 is a specific and highly effective retinoic acid receptor (RAR) antagonist[1][2]. AGN 193109 (GMP) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. AGN 193109 is the antidote for retinoic acidosis, that ameliorates the skin and mucosal toxicity.
Product Specifications
CAS Number
[171746-21-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
RAR/RXR
Type
GMP Small Molecules
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/agn-193109-gmp.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=C(C#CC2=CC=C3C(C)(C)CC=C(C4=CC=C(C)C=C4)C3=C2)C=C1
Molecular Formula
C28H24O2
Molecular Weight
392.50
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
Seal, light-resistant, store below -15°C
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
Available Sizes
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