Nor-Binaltorphimine

Nor-Binaltorphimine is a selective antagonist of kappa-opioid receptor. nor-Binaltorphimine has a long-lasting effect in vivo[1].

Product Specifications

CAS Number

[105618-26-6]

Product Name Alternative

Norbinaltorphimine; NorBNI

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/nor-binaltorphimine.html

Purity

98.70

Solubility

DMSO : ≥ 100 mg/mL|H2O : 33.08 mg/mL (ultrasonic; warming)

Smiles

O[C@]12[C@]34[C@](OC5=C(O)C=CC(C[C@@]2([H])N(CC4)CC6CC6)=C53)([H])C7=C(C8=C([C@@]9([H])[C@]%10%11[C@@](C8)([C@](CC%12=C%11C(O9)=C(C=C%12)O)([H])N(CC%10)CC%13CC%13)O)N7)C1

Molecular Formula

C40H43N3O6

Molecular Weight

661.79

Precautions

H315, H319, H335

References & Citations

[1]Spanagel R, et al. Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes. Eur J Pharmacol. 1994 Oct 24;264 (2) :157-62.