Nor-Binaltorphimine
Nor-Binaltorphimine is a selective antagonist of kappa-opioid receptor. nor-Binaltorphimine has a long-lasting effect in vivo[1].
Product Specifications
CAS Number
105618-26-6
Product Name Alternative
Norbinaltorphimine; NorBNI
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nor-binaltorphimine.html
Purity
98.70
Solubility
DMSO : ≥ 100 mg/mL|H2O : 33.08 mg/mL (ultrasonic; warming)
Smiles
O[C@]12[C@]34[C@](OC5=C(O)C=CC(C[C@@]2([H])N(CC4)CC6CC6)=C53)([H])C7=C(C8=C([C@@]9([H])[C@]%10%11[C@@](C8)([C@](CC%12=C%11C(O9)=C(C=C%12)O)([H])N(CC%10)CC%13CC%13)O)N7)C1
Molecular Formula
C40H43N3O6
Molecular Weight
661.79
Precautions
H315, H319, H335
References & Citations
[1]Spanagel R, et al. Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes. Eur J Pharmacol. 1994 Oct 24;264 (2) :157-62.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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