BMS-433771 (dihydrochloride hydrate)
BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV) . BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease[1][2].
Product Specifications
CAS Number
543700-67-0
UNSPSC
12352005
Target
RSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bms-433771-dihydrochloride-hydrate.html
Concentration
10mM
Purity
98.00
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N1C2CC2)N(CC3=NC4=CC=CC=C4N3CCCCO)C5=C1C=CN=C5.[H]Cl.[H]Cl.[H]O[H]
Molecular Formula
C21H27Cl2N5O3
Molecular Weight
468.38
References & Citations
[1]Christopher Cianci, et al. Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor. J Antimicrob Chemother|[2]Christopher Cianci, et al. Oral efficacy of a respiratory syncytial virus inhibitor in rodent models of infection. Antimicrob Agents Chemother. 2004 Jul;48 (7) :2448-54.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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