BMS-433771 (dihydrochloride hydrate)

BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV) . BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease[1][2].

Product Specifications

CAS Number

[543700-67-0]

UNSPSC

12352005

Target

RSV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bms-433771-dihydrochloride-hydrate.html

Concentration

10mM

Purity

98.00

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N1C2CC2)N(CC3=NC4=CC=CC=C4N3CCCCO)C5=C1C=CN=C5.[H]Cl.[H]Cl.[H]O[H]

Molecular Formula

C21H27Cl2N5O3

Molecular Weight

468.38

References & Citations

[1]Christopher Cianci, et al. Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor. J Antimicrob Chemother|[2]Christopher Cianci, et al. Oral efficacy of a respiratory syncytial virus inhibitor in rodent models of infection. Antimicrob Agents Chemother. 2004 Jul;48 (7) :2448-54.