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Dextran T2 (MW 2,000)

Dextran T2 (Dextran 2; Dextran T2 (MW 1600-2400) ) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM2), and Isomaltotriose (IM3) . Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity[1][2][3].

Product Specifications

CAS Number

[9004-54-0]

Product Name Alternative

Dextran 2; Dextran D2; Dextran T2 (MW 1600-2400)

UNSPSC

12352200

Hazard Statement

H303

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dextran-t2-mw-2-000.html

Solubility

10 mM in DMSO

Smiles

[DextranT2(MW2,000)]

Molecular Formula

(C6H10O5) n

Molecular Weight

1600-2400

Precautions

H303

References & Citations

[1]Chen F, et al. Preparation and application of dextran and its derivatives as carriers. Int J Biol Macromol. 2020 Feb 15;145:827-834.|[2]Cserr HF, et al. Bulk flow of interstitial fluid after intracranial injection of blue dextran 2000. Exp Neurol. 1974 Oct;45 (1) :50-60.|[3]Khalikova E, et al. Microbial dextran-hydrolyzing enzymes: fundamentals and applications. Microbiol Mol Biol Rev. 2005 Jun;69 (2) :306-25.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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