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FITC Anti-Human CD158/KIR2DL1 Antibody[HP-MA4]

Product Specifications

Background

CD158 molecules, also known as KIRs (killer cell immunoglobulin-like receptors), are a family of transmembrane proteins with either two (KIR2D) or three (KIR3D) Ig-like extracellular domains. Some KIRs with long cytoplasmic domains contain ITIMs and posses inhibitory functions and others with short cytoplasmic region lack ITIM and have activation functions. 14 polymorphic KIR genes have been reported in humans. CD158 is mainly expressed on a subset of NK cells and a small population of CD8+ T cells. HLA-C is the ligand of CD158a/h.

Abbreviation

CD158

Gene ID

3802;3810;3808;3806

UniProt

P43626; Q14953; Q14954

Host

Mouse

Reactivity

Human

Target

CD158a; CD158g; CD158h; KIR2DL1; KIR2DS1; KIR2DS3; KIR2DS5

Clonality

Monoclonal

Clone

HP-MA4

Conjugation

FITC

Applications

FCM

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2b, κ

Available Sizes

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