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Histone H2B (phospho-Ser14) rabbit pAb

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015],

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

Product Name Alternative

Histone H2B type 1-H (Histone H2B.j) (H2B/j)

UniProt

Q93079

Swiss Prot

Q93079

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized phosho peptide around human Histone H2B (Ser14)

Target

Histone H2B

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:1000-2000

Buffer

-20°C/1 year

Molecular Weight

18kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

18kD

Fragment

IgG

Subcellular Location

Nucleus. Chromosome.

Other Product Names

Histone H2B type 1-H (Histone H2B.j) (H2B/j)

Gene ID (Human)

8345

Available Sizes

Frequently Asked Questions

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