Lintopride (hydrochloride)
Lintopride hydrochloride, a benzamide, is a potent 5HT-4 antagonist with moderate 5HT-3 antagonist properties. Lintopride hydrochloride increases gastric emptying, stimulates antral and duodenal motility and accelerates intestinal transit in animal. Lintopride hydrochloride significantly increases the lower oesophageal sphincter (LOS) basal tone[1].
Product Specifications
CAS Number
[268548-31-8]
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/lintopride-hydrochloride.html
Smiles
O=C(NCC1=NCCN1CC)C2=CC(Cl)=C(N)C=C2OC.[H]Cl
Molecular Formula
C14H20Cl2N4O2
Molecular Weight
347.24
References & Citations
[1]Delvaux M, et al. The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther. 1995 Oct;9 (5) :563-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Apolipoprotein D; lactoferrin
Available Sizes
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