Methicillin (sodium salt)

Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation[1][2].

Product Specifications

CAS Number

[132-92-3]

Product Name Alternative

Meticillin (sodium)

UNSPSC

12352005

Hazard Statement

H315, H317, H319, H334, H335

Target

Antibiotic; Bacterial; Penicillin-binding protein (PBP)

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Methicillin-sodium-salt.html

Purity

98.12

Solubility

DMSO : 100 mg/mL

Smiles

O=C([C@H](N1C2=O)C(C)(S[C@@]1([C@@H]2NC(C3=C(C=CC=C3OC)OC)=O)[H])C)O[Na]

Molecular Formula

C17H19N2NaO6S

Molecular Weight

402.40

Precautions

H315, H317, H319, H334, H335

References & Citations

[1]Lincoln LJ, et al. Penicillinase-resistant penicillins plus gentamicin in experimental enterococcal endocarditis. Antimicrob Agents Chemother. 1977 Oct;12 (4) :484-9.|[2]Mandell GL, Vest TK. Killing of intraleukocytic Staphylococcus aureus by rifampin: in-vitro and in-vivo studies. J Infect Dis. 1972 May;125 (5) :486-90.