6-Chloro-9- (3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl) -9H-purine
Selected Variant
HY-W020420-01
Size: 25 mg
6-Chloro-9- (3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl) -9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
135473-15-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-chloro-9-3-5-di-o-benzoyl-2-deoxy-2-fluoro-beta-d-arabinofuranosyl-9h-purine.html
Solubility
10 mM in DMSO
Smiles
F[C@H]1[C@H](OC(C2=CC=CC=C2)=O)[C@@H](COC(C3=CC=CC=C3)=O)O[C@H]1N4C(N=CN=C5Cl)=C5N=C4
Molecular Formula
C24H18ClFN4O5
Molecular Weight
496.87
Precautions
H302, H315, H319, H335
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Price
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