3-Methyl-2-oxobutanoic acid

3-Methyl-2-oxobutanoic acid is a precursor of pantothenic acid in Escherichia coli.

Product Specifications

CAS Number

[759-05-7]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-Methyl-2-oxobutanoic_acid.html

Purity

99.10

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)C(C(O)=O)=O

Molecular Formula

C5H8O3

Molecular Weight

116.12

Precautions

H302, H315, H319, H335

References & Citations

[1]MAAS WK, et al. alpha-Ketoisovaleric acid, a precursor of pantothenic acid in Escherichia coli. J Bacteriol. 1953 Apr;65 (4) :388-93.|[2]Schauder P, et al. Oral administration of alpha-ketoisovaleric acid or valine in humans: blood kinetics and biochemical effects. J Lab Clin Med. 1984 Apr;103 (4) :597-605.|[3]Coitinho AS, et al. Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Res. 2001 Mar 9;894 (1) :68-73.