3-Methyl-2-oxobutanoic acid
3-Methyl-2-oxobutanoic acid is a precursor of pantothenic acid in Escherichia coli.
Product Specifications
CAS Number
759-05-7
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/3-Methyl-2-oxobutanoic_acid.html
Purity
99.10
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)C(C(O)=O)=O
Molecular Formula
C5H8O3
Molecular Weight
116.12
Precautions
H302, H315, H319, H335
References & Citations
[1]MAAS WK, et al. alpha-Ketoisovaleric acid, a precursor of pantothenic acid in Escherichia coli. J Bacteriol. 1953 Apr;65 (4) :388-93.|[2]Schauder P, et al. Oral administration of alpha-ketoisovaleric acid or valine in humans: blood kinetics and biochemical effects. J Lab Clin Med. 1984 Apr;103 (4) :597-605.|[3]Coitinho AS, et al. Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Res. 2001 Mar 9;894 (1) :68-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; Microbial Metabolite
Available Sizes
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