Candoxatril
Candoxatril is a neutral endopeptidase (NEP) inhibitor.
Product Specifications
CAS Number
123122-55-4
Product Name Alternative
UK 79300
UNSPSC
12352005
Target
Neprilysin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Candoxatril.html
Purity
99.56
Solubility
DMSO : 50 mg/mL (ultrasonic; warming)
Smiles
O=C(C1(CCCC1)C[C@@H](COCCOC)C(OC2=CC=C(CCC3)C3=C2)=O)N[C@H]4CC[C@@H](C(O)=O)CC4
Molecular Formula
C29H41NO7
Molecular Weight
515.64
References & Citations
[1]Bevan EG, et al. Candoxatril, a neutral endopeptidase inhibitor: efficacy and tolerability in essential hypertension. J Hypertens. 1992 Jul;10 (7) :607-13.|[2]M Aleksinskaya, et al. Neutral endopeptidase inhibitors SOL-1 and candoxatril counteract kidney fibrosis by reducing myofibroblast formation in mouse UUO model. Bmc Pharmacology & Toxicology , 2013 , 14 (1) :1-2.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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