Candoxatril
Candoxatril is a neutral endopeptidase (NEP) inhibitor.
Product Specifications
CAS Number
[123122-55-4]
Product Name Alternative
UK 79300
UNSPSC
12352005
Target
Neprilysin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Candoxatril.html
Purity
99.56
Solubility
DMSO : 50 mg/mL (ultrasonic; warming)
Smiles
O=C(C1(CCCC1)C[C@@H](COCCOC)C(OC2=CC=C(CCC3)C3=C2)=O)N[C@H]4CC[C@@H](C(O)=O)CC4
Molecular Formula
C29H41NO7
Molecular Weight
515.64
References & Citations
[1]Bevan EG, et al. Candoxatril, a neutral endopeptidase inhibitor: efficacy and tolerability in essential hypertension. J Hypertens. 1992 Jul;10 (7) :607-13.|[2]M Aleksinskaya, et al. Neutral endopeptidase inhibitors SOL-1 and candoxatril counteract kidney fibrosis by reducing myofibroblast formation in mouse UUO model. Bmc Pharmacology & Toxicology , 2013 , 14 (1) :1-2.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6252631-01 0.1 mL
CD62L (gp90 MEL, hLHRc, L Selectin, L-Selectin, LECAM-1, Lymph Node Homing Receptor, LNHR, Lymphocyte Adhesion Molecule 1, LYAM1, PLNHR, Selectin L, SELL, TQ1) (MaxLight 405)
Ask
View Details 
MBS6252631-02 5x 0.1 mL
CD62L (gp90 MEL, hLHRc, L Selectin, L-Selectin, LECAM-1, Lymph Node Homing Receptor, LNHR, Lymphocyte Adhesion Molecule 1, LYAM1, PLNHR, Selectin L, SELL, TQ1) (MaxLight 405)
Ask
View Details MBS7035654-01 0.02 mg
Recombinant Human Probable palmitoyltransferase ZDHHC1 (ZDHHC1)
Ask
View Details MBS7035654-02 0.1 mg
Recombinant Human Probable palmitoyltransferase ZDHHC1 (ZDHHC1)
Ask
View Details 
MBS7035654-03 5x 0.1 mg
Recombinant Human Probable palmitoyltransferase ZDHHC1 (ZDHHC1)
Ask
View Details 51955124 3x 1.0µg DNA
ZRANB3 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Ask
View Details