Fianlimab
Fianlimab (REGN3767) is a human monoclonal antibody that targets the immune checkpoint receptor LAG-3 on T cells and has anti-tumour activity[1].
Product Specifications
CAS Number
2126132-98-5
Product Name Alternative
REGN3767
UNSPSC
12352203
Target
LAG-3
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fianlimab.html
Purity
99.04
Solubility
10 mM in DMSO
Smiles
[Fianlimab]
Molecular Weight
(146.46 kDa)
References & Citations
[1]Omid Hamid, et al. Clinical activity of fianlimab (REGN3767), a human anti-LAG-3 monoclonal antibody, combined with cemiplimab (anti-PD-1) in patients (pts) with advanced melanoma.Meeting Abstract | 2021 ASCO Annual Meeting I.|[2]Burova E, et al., Preclinical Development of the Anti-LAG-3 Antibody REGN3767: Characterization and Activity in Combination with the Anti-PD-1 Antibody Cemiplimab in Human PD-1xLAG-3-Knockin Mice. Mol Cancer Ther. 2019 Nov;18 (11) :2051-2062.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
18613121 3x 1.0µg DNA
DSCC1 CRISPRa sgRNA lentivector (set of three targets)(Human)
Sign In for Pricing
View Details ![Rat Monoclonal IL-17RD/SEF Antibody (400210) [DyLight 405]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
FAB2276E 0.1 mL
Rat Monoclonal IL-17RD/SEF Antibody (400210) [DyLight 405]
Sign In for Pricing
View Details JL52453-01 48 Tests
Mouse Ribonucleoside-diphosphate Reductase Large Subunit (RRM1) ELISA Kit
Sign In for Pricing
View Details