Hypusine (dihydrochloride)
Product Specifications
UNSPSC Description
Hypusine dihydrochloride is a natural amino acid found only in the eukaryotic translation initiation factor 5A (eIF-5A). Hypusine is formed by the transfer of the butylamine portion from spermidine to the ϵ-amino group of a specific lysine residue of eIF-5A precursor and by the hydroxylation at carbon 2 of the incoming 4-aminobutyl moiety[1][2].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hypusine-dihydrochloride.html
Smiles
O=C([C@H](CCCCNC[C@@H](CCN)O)N)O.Cl.Cl
Molecular Weight
306.23
References & Citations
[1]Park MH, et al. Hypusine, a polyamine-derived amino acid critical for eukaryotic translation. J Biol Chem. 2018 Nov 30;293(48):18710-18718.|[2]Beninati S, et al. Tissue transglutaminase expression affects hypusine metabolism in BALB/c 3T3 cells. FEBS Lett. 1998 Oct 16;437(1-2):34-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122039/Hypusine-dihydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122039/
Clinical Information
No Development Reported
CAS Number
82310-93-8
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