CuATSM
CuATSM is a copper complex that scavenges free radicals, inhibits lipid peroxidation and ferroptosis. CuATSM exhibits antioxidant, anti-inflammatory and neuroprotective activities[1][2].
Product Specifications
CAS Number
68341-09-3
UNSPSC
12352300
Target
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cuatsm.html
Purity
99.13
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
CC1=[N]2[N-]C(NC)=[S][Cu+2]32[S]=C(NC)[N-][N]3=C1C
Molecular Formula
C8H14CuN6S2
Molecular Weight
321.91
References & Citations
[1]Zilka O, et al. Radical-Trapping Antioxidant Activity of Copper and Nickel Bis (Thiosemicarbazone) Complexes Underlies Their Potency as Inhibitors of Ferroptotic Cell Death. J Am Chem Soc. 2021 Nov 17;143 (45) :19043-19057.|[2]Shi X, et al., Neuroprotective effect of CuATSM in mice stroke model by ameliorating oxidative stress. Neurosci Res. 2021 May;166:55-61.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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