A-Raf Antibody

<strong>A-Raf Antibody </strong>_x000D_ <strong>Catalog number:</strong> B2015860_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 68 kDa._x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8° C_x000D_ <strong>Keywords:</strong> A-Raf Antibody_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Nekhoroshkova E, Albert S, Becker M, Rapp UR. A-RAF kinase functions in ARF6 regulated endocytic membrane traffic PLoS One. 2009;4(2):e4647._x000D_ 2: Molzan M, Kasper S, Röglin L, Skwarczynska M, Sassa T, Inoue T, Breitenbuecher F, Ohkanda J, Kato N, Schuler M, Ottmann C. Stabilization of physical RAF/14-3-3 interaction by cotylenin A as treatment strategy for RAS mutant cancers ACS Chem Biol. 2013 Sep 20;8(9):1869-75._x000D_ 3: Bronte F, Bronte G, Cusenza S, Fiorentino E, Rolfo C, Cicero G, Bronte E, Di Marco V, Firenze A, Angarano G, Fontana T, Russo A. Targeted therapies in hepatocellular carcinoma Curr Med Chem. 2014;21(8):966-74._x000D_ 4: Gentschev I, Fensterle J, Schmidt A, Potapenko T, Troppmair J, Goebel W, Rapp UR. Use of a recombinant Salmonella enterica serovar Typhimurium strain expressing C-Raf for protection against C-Raf induced lung adenoma in mice BMC Cancer. 2005 Feb 9;5:15._x000D_ 5: Tran G, Huynh TN, Paller AS. Langerhans cell histiocytosis: A neoplastic disorder driven by Ras-ERK pathway mutations J Am Acad Dermatol. 2018 Mar;78(3):579-590.e4._x000D_ 6: Maddahi A, Ansar S, Chen Q, Edvinsson L. Blockade of the MEK/ERK pathway with a raf inhibitor prevents activation of pro-inflammatory mediators in cerebral arteries and reduction in cerebral blood flow after subarachnoid hemorrhage in a rat model J Cereb Blood Flow Metab. 2011 Jan;31(1):144-54._x000D_ 7: Hu L, Li L, Yan C, Cao Y, Duan X, Sun J. Baicalin Inhibits Airway Smooth Muscle Cells Proliferation through the RAS Signaling Pathway in Murine Asthmatic Airway Remodeling Model Oxid Med Cell Longev. 2023 Feb 13;2023:4144138._x000D_ 8: Yeung K, Seitz T, Li S, Janosch P, McFerran B, Kaiser C, Fee F, Katsanakis KD, Rose DW, Mischak H, Sedivy JM, Kolch W. Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP Nature. 1999 Sep 9;401(6749):173-7._x000D_ 9: Zhang BH, Guan KL. Regulation of the Raf kinase by phosphorylation Exp Lung Res. 2001 Apr-May;27(3):269-95._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/8390681">10: Williams NG, Paradis H, Agarwal S, Charest DL, Pelech SL, Roberts TM. Raf-1 and p21v-ras cooperate in the activation of mitogen-activated protein kinase Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5772-6. </a>_x000D_ _x000D_ <strong>Products Related to A-Raf Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>