Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

AMPKα1 (phospho-Ser485) rabbit pAb

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Product Name Alternative

5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)

UniProt

Q13131

Swiss Prot

Q13131

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized phosho peptide around human AMPKα1 (Ser485)

Target

AMPKα1

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:1000-2000

Buffer

-20°C/1 year

Molecular Weight

65kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

65kD

Fragment

IgG

Subcellular Location

Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .

Other Product Names

5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)

Gene ID (Human)

5562

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

iFluor™ 488 Conjugated OGT Recombinant Rabbit Monoclonal Antibody [JB44-39]
HA720156F 100 µL

iFluor™ 488 Conjugated OGT Recombinant Rabbit Monoclonal Antibody [JB44-39]

Sign In for Pricing
View Details
DDX11 (Center) Rabbit Polyclonal Antibody
AP51215PU-N 400 µL

DDX11 (Center) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Syt6 Mouse Gene Knockout Kit (CRISPR)
KN517089 1 Kit

Syt6 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Phospho-p53 (S15) Recombinant Rabbit monoclonal Antibody
HA750772 100 µL

Phospho-p53 (S15) Recombinant Rabbit monoclonal Antibody

Sign In for Pricing
View Details
Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), 0.2mg/mL
BNUB0252-500 1x 500 µL

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), 0.2mg/mL

Sign In for Pricing
View Details
Fas Ligand (FASLG) Mouse Monoclonal Antibody [Clone ID: NOK-1]
AM26762RP-N 100 Tests

Fas Ligand (FASLG) Mouse Monoclonal Antibody [Clone ID: NOK-1]

Sign In for Pricing
View Details