Gpr35 modulator 1
Gpr35 modulator 1 (compound 1-18) is a potent modulator of Gpr35, with the IC50 of ≤ 100 nM in HEK293 cells stably transfected with human GPR35[1].
Product Specifications
CAS Number
2994189-01-2
UNSPSC
12352005
Target
GPR35
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gpr35-modulator-1.html
Smiles
O=C(C1=COC2=CC(C3=NN=NN3)=C(C=C21)F)NC4=CC=C(C=C4)OCC5=CC=C(C=C5Cl)F
Molecular Formula
C23H14ClF2N5O3
Molecular Weight
481.84
References & Citations
[1]Crossignal Therapeutics, Inc. Preparation of tetrazoles and related heterocycles as Gpr35 modulators useful in treatment of cancer. World Intellectual Property Organization, WO2023196538 A1 2023-10-12
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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