Kanosamine
Kanosamine (3-Amino-3-deoxyglucose) is an antibiotic against Saccharomyces cerevisiae and human pathogenic fungi Candida albicans. Kanosamine exhibits antifungal activity through inhibition of cell wall synthesis and inhibition of GlcN-6-P synthase with phosphorylated kanosamine-6-phosphate in cytoplasma[1][2].
Product Specifications
CAS Number
576-44-3
Product Name Alternative
3-Amino-3-deoxyglucose
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/kanosamine.html
Solubility
10 mM in DMSO
Smiles
O=C[C@H](O)[C@H]([C@H](O)[C@H](O)CO)N
Molecular Formula
C6H13NO5
Molecular Weight
179.17
Precautions
H302, H315, H319, H335
References & Citations
[1]Janiak AM, et al., Mechanism of antifungal action of kanosamine. Med Mycol. 2001 Oct;39 (5) :401-8.|[2]Iwai Y, Tet al., Studies on bacterial cell wall inhibitors. III. 3-amino-3-deoxy-D-glucose, an inhibitor of bacterial cell wall synthesis. Biochim Biophys Acta. 1977 Jun 23;498 (1) :223-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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