MJ33 (lithium salt)
MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6[1].
Product Specifications
CAS Number
[1007476-63-2]
UNSPSC
12352211
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mj33-lithium-salt.html
Purity
99.0
Solubility
DMSO : ≥ 0.25mg/mL|Ethanol : 2 mg/mL (ultrasonic; warming)
Smiles
O=P(OC)(OC(COCC(F)(F)F)COCCCCCCCCCCCCCCCC)O[Li]
Molecular Formula
C22H43F3LiO6P
Molecular Weight
498.48
References & Citations
[1]Fisher AB, Dodia C, Chander A, Jain M. A competitive inhibitor of phospholipase A2 decreases surfactant phosphatidylcholine degradation by the rat lung. Biochem J. 1992 Dec 1;288 (Pt 2) (Pt 2) :407-11.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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