(S) -AZD 6482
(S) -AZD6482 ((S) -KIN-193) is a highly effective and selective ATP-competitive inhibitor of PI3Kβ, exhibiting an IC (50) of 0.01 μM, and it can reduce insulin-induced glucose uptake by human adipocytes in vitro with an IC (50) of 4.4 μM.
Product Specifications
CAS Number
[1173900-37-2]
Product Name Alternative
(S) -KIN-193
UNSPSC
12352005
Hazard Statement
H302-H315-H320-H335
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/s-azd-6482.html
Smiles
O=C(C1=CC=CC=C1N[C@@H](C)C2=CC(C)=CN3C2=NC(N4CCOCC4)=CC3=O)O
Molecular Formula
C22H24N4O4
Molecular Weight
408.45
Precautions
P261-P280-P302+P352
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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