Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Robinin

Robinin is a flavonoid that can be extracted from the leaves of purple cowpea, inhibiting TGF-β, TLR4/NF-κB and TLR2-PI3k-AKT signaling pathways. Robinin exerts anti-inflammatory and anti-tumor effects. The combination of Robinin and Methotrexate reduces inflammation in experimental arthritis, Robinin can decrease the Doxorubicin (HY-15142A) induced cardiac toxicity effect[1][2][3][4].

Product Specifications

CAS Number

301-19-9

UNSPSC

12352005

Hazard Statement

H302

Target

Apoptosis; Toll-like Receptor (TLR)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/robinin.html

Purity

99.09

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C1C(O[C@H]2[C@@H]([C@H]([C@H]([C@@H](CO[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)O2)O)O)O)=C(C4=CC=C(O)C=C4)OC5=CC(O[C@H]6[C@@H]([C@@H]([C@H]([C@H](C)O6)O)O)O)=CC(O)=C15

Molecular Formula

C33H40O19

Molecular Weight

740.66

Precautions

H302

References & Citations

[1]Janeesh PA, et al. Robinin modulates TLR/NF-κB signaling pathway in oxidized LDL induced human peripheral blood mononuclear cells. Int Immunopharmacol. 2014 Jan;18 (1) :191-7.|[2]wenwen Zhang, et al. Robinin inhibits pancreatic cancer cell proliferation, EMT and inflammation via regulating TLR2-PI3k-AKT signaling pathway, 10 May 2023.|[3]Tsiklauri L, et al. Bioflavonoid Robinin from Astragalus falcatus Lam. Mildly Improves the Effect of Metothrexate in Rats with Adjuvant Arthritis. Nutrients. 2021 Apr 13;13 (4) :1268.|[4]Janeesh PA, et al. Robinin modulates doxorubicin-induced cardiac apoptosis by TGF-β1 signaling pathway in Sprague Dawley rats. Biomed Pharmacother. 2014 Oct;68 (8) :989-98.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

TLR2; TLR4

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CBR1 Antibody
CSB-PA232262-01 50 μL

CBR1 Antibody

Sign In for Pricing
View Details
CBR1 Antibody
CSB-PA232262-02 100 µL

CBR1 Antibody

Sign In for Pricing
View Details
Endo β-N-Acetylglucosaminidase (ENGASE) Human ELISA Kit
D1587 96 Tests

Endo β-N-Acetylglucosaminidase (ENGASE) Human ELISA Kit

Sign In for Pricing
View Details
5430402E10Rik Protein Vector (Mouse) (pPM-C-His)
PV149901 500 ng

5430402E10Rik Protein Vector (Mouse) (pPM-C-His)

Sign In for Pricing
View Details
TIE1 (Tyrosine Kinase with Immunoglobulin-like and EGF-like Domains 1, JTK14, TIE) (APC)
MBS6167777-01 0.1 mL

TIE1 (Tyrosine Kinase with Immunoglobulin-like and EGF-like Domains 1, JTK14, TIE) (APC)

Sign In for Pricing
View Details
TIE1 (Tyrosine Kinase with Immunoglobulin-like and EGF-like Domains 1, JTK14, TIE) (APC)
MBS6167777-02 5x 0.1 mL

TIE1 (Tyrosine Kinase with Immunoglobulin-like and EGF-like Domains 1, JTK14, TIE) (APC)

Sign In for Pricing
View Details