N-Boc-cis-4-Hydroxy-D-proline
N-Boc-cis-4-Hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N-Boc-cis-4-Hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the Synthesis of ADCs or PROTACs.
Product Specifications
CAS Number
[135042-12-5]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-boc-cis-4-hydroxy-d-proline.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)(C)OC(N1[C@H](C[C@H](C1)O)C(O)=O)=O
Molecular Formula
C10H17NO5
Molecular Weight
231.25
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
Available Sizes
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