Sheep anti Human Rhombotin 2
Product Specifications
Background
Two homologues of the rhombotin gene have now been isolated. One of these, designated Rhom-2, is located on Human chromosome 11 at band 11p13, where a cluster of T-cell leukemia-specific translocations occur; all translocation breakpoints at 11p13 are upstream of the Rhom-2 gene. Human and mouse Rhom-2 are highly conserved and, like rhombotin, encode two tandem cysteine-rich LIM domains. Rhom-2 mRNA is expressed in early mouse development in central nervous system, lung, kidney, liver, and spleen but only very low levels occur in thymus. The Rhom-2 gene is such a common site of chromosomal damage in T-cell tumors. Chromosome bands 11p15 (rhombotin) and 11p13 (Rhom-2) are consistent sites of chromosome translocation in T-cell leukemia, with the 11p15 target more rarely involved.
Synonyms
LIM Domain only Protein, cysteine-rich Protein TTG-2, T-Cell translocation Protein 2
UniProt
P25791 (Human)
Host
Sheep
Species Reactivity
Human
Isotype
IgG
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Field of Research
Inflammation and Immunology
Purification Method
Ammonium Sulfate Precipitation
Assay Principle
Western Blots at 1-10 µg /mL
Stability
See expiration date on vial
Concentration
See vial for Concentration
Form
Provided as solution in phosphate buffered saline with 0,08% sodium azide
Precautions
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
Shipping Conditions
Room Temperature
Storage Conditions
Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
Functional Analysis
WB
CAS Number
9007-83-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
