BE 24566B
BE 24566B is a polyketide fungal metabolite originally isolated from S. violaceusniger. It is active against B. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, and S. thermophilus (MICs=1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/mL, respectively) . BE 24566B is an endothelin (ET) receptor antagonist (IC50s=11 and 3.9 μM for ETA and ETB receptors, respectively) .
Product Specifications
CAS Number
149466-04-6
Product Name Alternative
L-755,805
UNSPSC
12352005
Target
Bacterial; Endothelin Receptor
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/be-24566b.html
Smiles
OC(C(C(C1=C2O)=O)=C(C(C)(C1=CC(O)=C2)C)C=C3C[C@@]4(C)O5)=C3[C@@]5([H])C(C(O4)=CC(O)=C6)=C6C
Molecular Formula
C27H24O7
Molecular Weight
460.48
References & Citations
[1]Kojiri, et al. BE-24566B, a new antibiotic produced by Streptomyces violaceusniger. J. Antibiot. (Tokyo) 48 (12), 1506-1508 (1995) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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