OBA-09

OBA-09, a simple ester of pyruvate and salicylic acid, is potent multi-modal neuroprotectant. OBA-09 has anti-oxidative and anti-inflammatory effects[1][2].

Product Specifications

CAS Number

[856095-68-6]

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/OBA-09.html

Concentration

10mM

Purity

99.17

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(O)C1=CC=CC=C1OC(C(C)=O)=O

Molecular Formula

C10H8O5

Molecular Weight

208.17

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Kim SW, et al. Robust protective effects of a novel multimodal neuroprotectant oxopropanoyloxy benzoic acid (a salicylic acid/pyruvate ester) in the postischemic brain. Mol Pharmacol. 2011 Feb;79 (2) :220-8.|[2]Lee HK, et, al. Anti-inflammatory effects of OBA-09, a salicylic acid/pyruvate ester, in the postischemic brain. Brain Res. 2013 Aug 28;1528:68-79.