Norstictic acid

Norstictic acid is a potent and selective allossteric transcriptional regulator. Norstictic acid shows anticancer activity. Norstictic acid shows antioxidant activity and antimicrobial activity[1][2][3][4].

Product Specifications

CAS Number

[571-67-5]

UNSPSC

12352005

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/norstictic-acid.html

Purity

96.6

Solubility

10 mM in DMSO

Smiles

O=CC1=C(OC(C(OC2=O)=C(C)C(O)=C34)=C3C(O)OC4=O)C2=C(C)C=C1O

Molecular Formula

C18H12O9

Molecular Weight

372.28

References & Citations

[1]Garlick JM, et al. Norstictic Acid Is a Selective Allosteric Transcriptional Regulator. J Am Chem Soc. 2021 Jun 30;143 (25) :9297-9302.|[2]Ebrahim HY, et al. Norstictic Acid Inhibits Breast Cancer Cell Proliferation, Migration, Invasion, and In Vivo Invasive Growth Through Targeting C-Met. Phytother Res. 2016 Apr;30 (4) :557-66.|[3]Ranković B, et al. Biological activities of Toninia candida and Usnea barbata together with their norstictic acid and usnic acid constituents. Int J Mol Sci. 2012 Nov 12;13 (11) :14707-22.|[4]Tay T, et al. Evaluation of the antimicrobial activity of the acetone extract of the lichen Ramalina farinacea and its (+) -usnic acid, norstictic acid, and protocetraric acid constituents. Z Naturforsch C J Biosci. 2004 May-Jun;59 (5-6) :384-8.