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HSK0935

HSK0935 is a potent, highly selective and orally available SGLT2 inhibitor with an IC50 of 1.3 nM. Antihyperglycemic activities[1].

Product Specifications

CAS Number

1638851-44-1

UNSPSC

12352005

Target

SGLT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/HSK0935.html

Purity

96.63

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC(C=C1)=C(CC2=CC=C(OCC)C=C2)C=C1[C@@]3(OC4)[C@H](O)[C@@H](O)[C@H](O)[C@@]4(OC)O3

Molecular Formula

C22H25ClO7

Molecular Weight

436.88

References & Citations

[1]Li Y, et al. Discovery of a Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor (HSK0935) for the Treatment of Type 2 Diabetes. J Med Chem. 2017 May 25;60 (10) :4173-4184.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

SGLT2

Available Sizes

Frequently Asked Questions

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