HSK0935
HSK0935 is a potent, highly selective and orally available SGLT2 inhibitor with an IC50 of 1.3 nM. Antihyperglycemic activities[1].
Product Specifications
CAS Number
1638851-44-1
UNSPSC
12352005
Target
SGLT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/HSK0935.html
Purity
96.63
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC(C=C1)=C(CC2=CC=C(OCC)C=C2)C=C1[C@@]3(OC4)[C@H](O)[C@@H](O)[C@H](O)[C@@]4(OC)O3
Molecular Formula
C22H25ClO7
Molecular Weight
436.88
References & Citations
[1]Li Y, et al. Discovery of a Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor (HSK0935) for the Treatment of Type 2 Diabetes. J Med Chem. 2017 May 25;60 (10) :4173-4184.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SGLT2
Available Sizes
Frequently Asked Questions
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