HLCL-61
Product Specifications
UNSPSC Description
HLCL-61 is a first-in-class small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5).
Target Antigen
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hlcl-61.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC=C1CNCC2=CC3=C(C=C2)N(CC)C4=C3C=CC=C4
Molecular Weight
344.45
References & Citations
[1]Tarighat SS, et al. The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation. Leukemia. 2016 Apr;30(4):789-99.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100025/HLCL-61-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100025/
Clinical Information
No Development Reported
CAS Number
586395-74-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
