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Dapaconazole

Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM[1].

Product Specifications

CAS Number

1269726-67-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dapaconazole.html

Purity

99.76

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(C1=CC=C(COC(C2=CC=C(Cl)C=C2Cl)CN3C=CN=C3)C=C1)(F)F

Molecular Formula

C19H15Cl2F3N2O

Molecular Weight

415.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Juliana SP, et al. Pharmacokinetics of Dapaconazole, A Novel Antifungal Agent, in Beagle Dogs and Inhibition of Cytochrome P450 Family 51. J Eur Acad Dermatol Venereol. 2018 Jun 10.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Isoform

CYP26

Available Sizes

Frequently Asked Questions

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