COX-2-IN-34
COX-2-IN-34 (compound 8a) is a selective and orally active inhibitor of COX-2 , with an IC50 of 0.42 μM. COX-2-IN-34 has no gastric ulcer toxicity but has anti-inflammatory effects[1].
Product Specifications
CAS Number
[2788578-71-0]
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-2-in-34.html
Purity
98.87
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=CC=C1O)C2=CC=CC(O)=C2O
Molecular Formula
C13H11NO4
Molecular Weight
245.23
References & Citations
[1]1. 1. Min Xin, et al. Synthesis and biological evaluation of resveratrol amide derivatives as selective COX-2 inhibitors. Chemico-Biological Interactions. Volume 380, 1 August 2023, 110522.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
Available Sizes
Curated Selection
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