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COX-2-IN-34

COX-2-IN-34 (compound 8a) is a selective and orally active inhibitor of COX-2 , with an IC50 of 0.42 μM. COX-2-IN-34 has no gastric ulcer toxicity but has anti-inflammatory effects[1].

Product Specifications

CAS Number

[2788578-71-0]

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cox-2-in-34.html

Purity

98.87

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=CC=C1O)C2=CC=CC(O)=C2O

Molecular Formula

C13H11NO4

Molecular Weight

245.23

References & Citations

[1]1. 1. Min Xin, et al. Synthesis and biological evaluation of resveratrol amide derivatives as selective COX-2 inhibitors. Chemico-Biological Interactions. Volume 380, 1 August 2023, 110522.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

COX-2

Available Sizes

Curated Selection

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