Suc-Ala-Glu-Pro-Phe-pNA (TFA)
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc[1][2].
Product Specifications
Product Name Alternative
Suc-AEPF-pNA (TFA)
UNSPSC
12171500
Target
Biochemical Assay Reagents
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/suc-ala-glu-pro-phe-pna-tfa.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CCC1)[C@@H]1C(N[C@H](C(NC(C=C2)=CC=C2[N+]([O-])=O)=O)CC3=CC=CC=C3)=O)[C@H](CCC(O)=O)NC([C@H](C)NC(CCC(O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C34H39F3N6O13
Molecular Weight
796.70
References & Citations
[1]Subedi A, et al. Discovery of novel selenium derivatives as Pin1 inhibitors by high-throughput screening. Biochem Biophys Res Commun. 2016 Jun 3;474 (3) :528-533. |[2]Liu C, et al. Imazamethabenz inhibits human breast cancer cell proliferation, migration and invasion via combination with Pin1. Mol Med Rep. 2017 May;15 (5) :3210-3214.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400806-100 1x 100 µL
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741073-500 1x 500 µL
HLA-Aw32 & HLA-A25 (MHC I) (CATA-1), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
