MG-V-53
MG-V-53 is a potent small molecule V domain T-cell activating immunoglobulin suppressor (VISTA) inhibitor with IC50 value of 121 nM. MG-V-53 has antitumor activity[1].
Product Specifications
CAS Number
[920157-23-9]
UNSPSC
12352005
Target
VISTA
Type
Reference compound
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mg-v-53.html
Purity
90.0
Smiles
FC1C=CC(C2C=CC(OCCNC(CC3C=CC(F)=CC=3)=O)=NN=2)=CC=1
Molecular Formula
C20H17F2N3O2
Molecular Weight
369.37
References & Citations
[1]Abdel-Rahman SA, et al. Small molecules from antibody pharmacophores (SMAbPs) as a hit identification workflow for immune checkpoints. Sci Adv. 2024 Oct 18;10 (42) :eadq5540.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Dedicated for Diverse Library
Clinical Information
No Development Reported
Curated Selection
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