2'-Deoxyadenosine-5'-monophosphate-13C10,15N5 (dilithium)
Product Specifications
UNSPSC Description
2'-Deoxyadenosine-5'-monophosphate-13C10,15N5 dilithium is 13C and 15N-labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
Target Antigen
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease;Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-deoxyadenosine-5-monophosphate-13c10-15n5-dilithium.html
Solubility
10 mM in DMSO
Smiles
O=P(O[Li])(O[Li])O[13CH2][13C@H]1O[13C@@H]([15N]2[13C]3=[15N][13CH]=[15N][13C]([15NH2])=[13C]3[15N]=[13CH]2)[13CH2][13C@@H]1O
Molecular Weight
357.98
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Katsuya Narumi, et al. Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP. PLoS One. 2019 Oct 21;14(10):e0223892.|[3]V Duarte, et al. Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine. Nucleic Acids Res. 1999 Jan 15;27(2):496-502.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W016009S4/2-Deoxyadenosine-5-monophosphate-13C10-15N5-dilithium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W016009S4/
Clinical Information
No Development Reported
CAS Number
2483830-51-7
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