Uvaol diacetate
Uvaol diacetate (Compound 5) is a triterpenoid derived from the leaves of Nerium oleunder L. and is an analog of Uvaol. Uvaol has protective effects against DNA damage and can also induce apoptosis in cancer cells[1][2].
Product Specifications
CAS Number
157000-65-2
UNSPSC
12352211
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/uvaol-diacetate.html
Solubility
10 mM in DMSO
Smiles
CC(OC[C@]12[C@]([C@H]([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@]4(C)[C@@](C(C)([C@H](CC4)OC(C)=O)C)([H])CC5)([H])[C@]5(C)[C@]3(C)CC1)=O
Molecular Formula
C34H54O4
Molecular Weight
526.79
References & Citations
[1]Siddiqui, et al. Kaneric Acid, a New Triterpene from the Leaves of Nerium oleander. Journal of Natural Products. 1986; 49 (6) :1086–1090.|[2]Martín R, et al. Natural triterpenic diols promote apoptosis in astrocytoma cells through ROS-mediated mitochondrial depolarization and JNK activation. PLoS One. 2009 Jun 22;4 (6) :e5975.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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