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Uvaol diacetate

Uvaol diacetate (Compound 5) is a triterpenoid derived from the leaves of Nerium oleunder L. and is an analog of Uvaol. Uvaol has protective effects against DNA damage and can also induce apoptosis in cancer cells[1][2].

Product Specifications

CAS Number

157000-65-2

UNSPSC

12352211

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/uvaol-diacetate.html

Solubility

10 mM in DMSO

Smiles

CC(OC[C@]12[C@]([C@H]([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@]4(C)[C@@](C(C)([C@H](CC4)OC(C)=O)C)([H])CC5)([H])[C@]5(C)[C@]3(C)CC1)=O

Molecular Formula

C34H54O4

Molecular Weight

526.79

References & Citations

[1]Siddiqui, et al. Kaneric Acid, a New Triterpene from the Leaves of Nerium oleander. Journal of Natural Products. 1986; 49 (6) :1086–1090.|[2]Martín R, et al. Natural triterpenic diols promote apoptosis in astrocytoma cells through ROS-mediated mitochondrial depolarization and JNK activation. PLoS One. 2009 Jun 22;4 (6) :e5975.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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