Benzylacetone

Benzylacetone is an aromatic compound from agarwood[1]. Benzylacetone exhibits potent and reversible antityrosinase (mushroom) activity, with IC50s of 2.8 mM and 0.6 mM for monophenolase and diphenolase, respectively[2]. Benzylacetone has appetite-enhancing and locomotor-reducing effects[3].

Product Specifications

CAS Number

[2550-26-7]

Product Name Alternative

4-Penylbutan-2-one

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Tyrosinase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/benzylacetone.html

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(CCC1=CC=CC=C1)=O

Molecular Formula

C10H12O

Molecular Weight

148.21

Precautions

H315, H319

References & Citations

[1]Takamatsu S, et al. Agarotetrol: a source compound for low molecular weight aromatic compounds from agarwood heating. J Nat Med. 2018 Mar;72 (2) :537-541.|[2]Liu X, et al. Inhibition effects of benzylideneacetone, benzylacetone, and 4-phenyl-2-butanol on the activity of mushroom tyrosinase. J Biosci Bioeng. 2015 Mar;119 (3) :275-9.|[3]Ogawa K, et al. Appetite-Enhancing Effects: The Influence of Concentrations of Benzylacetone and trans-Cinnamaldehyde and Their Inhalation Time, as Well as the Effect of Aroma, on Body Weight in Mice. Biol Pharm Bull. 2016;39 (5) :794-8.