PACAP38 (Human)

<strong>PACAP38 (Human)</strong> <strong>Catalog number:</strong> MDP0609 <strong>CAS Number: </strong>N/A <strong>Sequence: </strong>His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 4534 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Ashina H, Guo S, Vollesen ALH, Ashina M. PACAP38 in human models of primary headaches J Headache Pain. 2017 Nov 23;18(1):110. 2: Vollesen ALH, Ashina M. PACAP38: Emerging Drug Target in Migraine and Cluster Headache Headache. 2017 May;57 Suppl 2:56-63. 3: Schytz HW. Investigation of carbachol and PACAP38 in a human model of migraine Dan Med Bull. 2010 Dec;57(12):B4223. 4: Wojcieszak J, Zawilska JB. PACAP38 and PACAP6-38 exert cytotoxic activity against human retinoblastoma Y79 cells J Mol Neurosci. 2014 Nov;54(3):463-8. 5: Velasco ER, Florido A, Flores Á, Senabre E, Gomez-Gomez A, Torres A, Roca A, Norrholm S, Newman EL, Das P, Ross RA, Lori A, Pozo OJ, Ressler KJ, Garcia-Esteve LL, Jovanovic T, Andero R. PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus Nat Commun. 2022 Jul 28;13(1):4374. 6: Guo S. The role of genetics on migraine induction triggered by CGRP and PACAP38 Dan Med J. 2017 Mar;64(3):B5351. 7: Rubio-Beltrán E, Correnti E, Deen M, Kamm K, Kelderman T, Papetti L, Vigneri S, MaassenVanDenBrink A, Edvinsson L; European Headache Federation School of Advanced Studies (EHF-SAS). PACAP38 and PAC(1) receptor blockade: a new target for headache? J Headache Pain. 2018 Aug 7;19(1):64. 8: Patko E, Szabo E, Toth D, Tornoczky T, Bosnyak I, Vaczy A, Atlasz T, Reglodi D. Distribution of PACAP and PAC1 Receptor in the Human Eye J Mol Neurosci. 2022 Nov;72(11):2176-2187. 9: Yan BM, Gibson Depoy EM, Ahmad A, Nahas SJ. Biomarkers in Migraine Neurol India. 2021 Mar-Apr;69(Supplement):S17-S24. <a href="https://pubmed.ncbi.nlm.nih.gov/27084887">10: Vollesen AL, Guo S, Ashina M. PACAP38 dose-response pilot study in migraine patients Cephalalgia. 2017 Apr;37(4):391-395. </a> <br><strong>Products Related to PACAP38 (Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>