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Octenidine (saccharin)

Octenidine saccharin is a potent antibacterial agent, possessing activity against multidrug-resistant Gram-negative pathogens. Octenidine saccharin can inhibit the expression of biofilm genes and destroy the formation of biofilms[1][3].

Product Specifications

CAS Number

86767-75-1

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/octenidine-saccharin.html

Smiles

O=C1NS(=O)(C2=C1C=CC=C2)=O.CCCCCCCC/N=C(C=C3)/C=CN3CCCCCCCCCCN(C=C/4)C=CC4=N/CCCCCCCC.O=C5NS(=O)(C6=C5C=CC=C6)=O

Molecular Formula

C50H72N6O6S2

Molecular Weight

917.27

References & Citations

[1]Alvarez-Marin R, et al. Antimicrobial activity of octenidine against multidrug-resistant Gram-negative pathogens. Eur J Clin Microbiol Infect Dis. 2017 Dec;36 (12) :2379-2383.|[2]Conceição T, et al. Efficacy of octenidine against antibiotic-resistant Staphylococcus aureus epidemic clones. J Antimicrob Chemother. 2016 Oct;71 (10) :2991-4.|[3]Huang J, et al. Octenidine dihydrochloride treatment of a meticillin-resistant Staphylococcus aureus biofilm-infected mouse wound. J Wound Care. 2021 Feb 2;30 (2) :106-114.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 4

Frequently Asked Questions

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