Octenidine (saccharin)
Octenidine saccharin is a potent antibacterial agent, possessing activity against multidrug-resistant Gram-negative pathogens. Octenidine saccharin can inhibit the expression of biofilm genes and destroy the formation of biofilms[1][3].
Product Specifications
CAS Number
86767-75-1
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/octenidine-saccharin.html
Smiles
O=C1NS(=O)(C2=C1C=CC=C2)=O.CCCCCCCC/N=C(C=C3)/C=CN3CCCCCCCCCCN(C=C/4)C=CC4=N/CCCCCCCC.O=C5NS(=O)(C6=C5C=CC=C6)=O
Molecular Formula
C50H72N6O6S2
Molecular Weight
917.27
References & Citations
[1]Alvarez-Marin R, et al. Antimicrobial activity of octenidine against multidrug-resistant Gram-negative pathogens. Eur J Clin Microbiol Infect Dis. 2017 Dec;36 (12) :2379-2383.|[2]Conceição T, et al. Efficacy of octenidine against antibiotic-resistant Staphylococcus aureus epidemic clones. J Antimicrob Chemother. 2016 Oct;71 (10) :2991-4.|[3]Huang J, et al. Octenidine dihydrochloride treatment of a meticillin-resistant Staphylococcus aureus biofilm-infected mouse wound. J Wound Care. 2021 Feb 2;30 (2) :106-114.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
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