Peptide A5K (acetate)
Peptide A5K (INF7-A5K-TAT) acetate is an amphiphilic peptide derived from the HA2-TAT fusion scaffold. Peptide A5K acetate can non-covalently bind to CRISPR ribonucleoproteins and efficiently deliver them to cells, such as primary human T cells, B cells, and NK cells. Peptide A5K acetate enables low-toxicity, precise, and multiplex genome editing, holding great application potential in the field of cell therapy[1].
Product Specifications
Product Name Alternative
INF7-A5K-TAT (acetate)
UNSPSC
12352209
Target
Biochemical Assay Reagents
Type
Peptides
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/peptide-a5k-acetate.html
Solubility
10 mM in DMSO
Smiles
O=C(CN)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CC1=CC=C(O)C=C1)=O)=O)CC2=CC=C(O)C=C2)=O)CC3=CNC4=CC=CC=C34)=O)=O)CC(O)=O)=O)[C@H](CC)C)=O)CCSC)=O)=O)CCC(O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)CC(N)=O)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CC7=CC=CC=C7)=O)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CCCCN)=O)CCC(O)=O)=O)CC8=CC=CC=C8)=O)CC(C)C.CC(O)=O.[x]
Molecular Formula
C182H275N55O48S.xC2H4O2
Molecular Weight
4033.54 (free acid)
References & Citations
[1]Dana V Foss, et al. Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nat Biomed Eng. 2023 May;7 (5) :647-660.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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