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EDTA (disodium)

EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.

Product Specifications

CAS Number

[139-33-3]

Product Name Alternative

Ethylenediaminetetraacetic acid (disodium)

UNSPSC

12352200

Hazard Statement

H302+H332, H318, H373

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/edta-disodium.html

Purity

99.2

Solubility

H2O : 20 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(O)CN(CC(O)=O)CCN(CC(O[Na])=O)CC(O[Na])=O

Molecular Formula

C10H14N2Na2O8

Molecular Weight

336.21

Precautions

H302+H332, H318, H373

References & Citations

Environ Sci Technol. 2017 Dec 5;51(23):13938-13948.|Adv Sci (Weinh). 2022 Dec 12;e2204998.|bioRxiv. 2023 Sep 8.|Cell Immunol. 2023 Nov 2, 104781.|Colloids Surf B Biointerfaces. 2023 Dec 2, 113680.|Int J Biol Macromol. 2022.|Molecules. 2024 Jul 30;29(15):3590.|Nucleic Acids Res. 2024 Nov 30:gkae1112.|Biomed Pharmacother. 2019 Jan;109:2427-2433. |Molecules. 2021 Aug 24;26(17):5115.|Research Square Preprint. 2021 Oct.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Biochemical Assay Reagents

Clinical Information

Phase 4

Citation 01

Environ Sci Technol. 2017 Dec 5;51 (23) :13938-13948.|Adv Sci (Weinh) . 2023 Feb;10 (4) :e2204998.|Adv Sci (Weinh) . 2024 Dec 25:e2411261.|Adv Sci (Weinh) . 2025 Feb 8:e2415229.|Ann Med. 2025 Dec;57 (1) :2548045.|bioRxiv. 2023 Sep 8.|BMC Med Genomics. 2025 Aug 9;18 (1) :128.|Bone Res. 2025 Mar 3;13 (1) :30.|Cell Immunol. 2024 Jan-Feb:395-396:104781.|Colloids Surf B Biointerfaces. 2024 Feb:234:113680.|EMBO Mol Med. 2025 Oct 15.|Food Qual Saf. 2025 Aug 4.|Int J Biol Macromol. 2023 Jan 15:225:1182-1192.|Int J Biol Macromol. 2025 May 7:144068.|Int J Biol Macromol. 2026 Jan;335 (Pt 2) :149182.|J Extracell Vesicles. 2025 Sep;14 (9) :e70162.|J Nanobiotechnology. 2025 Mar 6;23 (1) :175.|J Orthop Surg Res. 2025 Apr 22;20 (1) :403.|Molecules. 2024 Jul 30;29 (15) :3590.|Nat Immunol. 2025 Oct;26 (10) :1660-1672.|Neuron. 2025 Jul 29:S0896-6273 (25) 00509-4.|Nucleic Acids Res. 2024 Nov 30:gkae1112.

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