Tridihexethyl (chloride)

Tridihexethyl (Pathilon) chloride is an orally active anticholinergic agent and mAChR antagonist, shows activities of antimuscarinic and anticholinergic. Tridihexethyl chloride shows pronounced antispasmodic and antisecretory effects on the gastrointestinal tract. Tridihexethyl chloride can be used in studies of peptic ulcer disease and acquired nystagmus [1][2].

Product Specifications

CAS Number

[4310-35-4]

Product Name Alternative

Pathilon (chloride)

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tridihexethyl-chloride.html

Purity

96.45

Solubility

DMSO : 1 mg/mL (ultrasonic; warming)

Smiles

OC(CC[N+](CC)(CC)CC)(C1CCCCC1)C2=CC=CC=C2.[Cl-]

Molecular Formula

C21H36ClNO

Molecular Weight

353.97

References & Citations

[1]Jabbari B, et al. ffectiveness of trihexyphenidyl against pendular nystagmus and palatal myoclonus: evidence of cholinergic dysfunction. Mov Disord. 1987;2 (2) :93-8.|[2]Leigh RJ, et al. Effect of anticholinergic agents upon acquired nystagmus: a double-blind study of trihexyphenidyl and tridihexethyl chloride. Neurology. 1991 Nov;41 (11) :1737-41.