IV-361
IV-361 is an orally active and selective CDK7 inhibitor (Ki≤50 nM) . IV-361 has anti-cancer activity (US20190256531A1) [1].
Product Specifications
CAS Number
[2055741-39-2]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iv-361.html
Purity
99.60
Solubility
DMSO : 90 mg/mL (ultrasonic)
Smiles
O=C(N(C1)C(C)(C)C2=C1C(NC(C3([Si](C)(C)C)CCC3)=O)=NN2)NC4=CC(F)=CC=C4C
Molecular Formula
C23H32FN5O2Si
Molecular Weight
457.62
References & Citations
[1]Noriaki Iwase, et al. Substituted dihydropyrrolopyrazole derivative. US20190256531A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2; CDK7
Available Sizes
Curated Selection
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