5-HT1A modulator 2 (hydrochloride)
5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT (HY-112061), is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding[1].
Product Specifications
CAS Number
[3880-76-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-ht1a-modulator-2-hydrochloride.html
Concentration
10mM
Purity
99.69
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1CC2=C(C=CC=C2OC)CC1.[H]Cl
Molecular Formula
C11H16ClNO
Molecular Weight
213.70
Precautions
H302, H315, H319, H335
References & Citations
[1]Naiman, N., et al. 2- (Alkylamino) tetralin derivatives: interaction with 5-HT1A serotonin binding sites. Journal of Medicinal Chemistry, 1989;32 (1), 253–256.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor
Available Sizes
Curated Selection
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