17β-HSD5 inhibitor 2
17β-HSD5 inhibitor 2 (Compound 30) is an inhibitor for 17β-hydroxysteroid dehydrogenases 5 (17β-HSD 5) with IC50 of 40 nM[1].
Product Specifications
CAS Number
1106941-19-8
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
FC(F)(F)C1=CC2=C(N(C3=CC=CC(C(OCC)=O)=C3)C(C4=CC=NC=C4)=N2)C=C1
Molecular Formula
C22H16F3N3O2
Molecular Weight
411.38
References & Citations
[1]Marchais-Oberwinkler S, et al., 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development. J Steroid Biochem Mol Biol. 2011 May;125 (1-2) :66-82.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KHK-C
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